SOCS6 Antikörper (AA 21-120) (Alexa Fluor 488)

Produktnummer ABIN6977286

Produktdetails anti-SOCS6 Antikörper (Alexa Fluor 488)

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Bindungsspezifität: AA 21-120

Reaktivität: Maus, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Huhn, Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOCS6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6 (SOCS6 Produkte)

Synonyme: CIS-4 antikoerper, CIS4 antikoerper, HSPC060 antikoerper, SOCS-4 antikoerper, SOCS-6 antikoerper, SOCS4 antikoerper, SSI4 antikoerper, STAI4 antikoerper, STATI4 antikoerper, socs6 antikoerper, MGC81477 antikoerper, SOCS6 antikoerper, 1500012M23Rik antikoerper, 5830401B18Rik antikoerper, AI447482 antikoerper, Cis4 antikoerper, Cish4 antikoerper, Socs4 antikoerper, socs6l antikoerper, zgc:64107 antikoerper, wu:fb77f06 antikoerper, suppressor of cytokine signaling 6 antikoerper, suppressor of cytokine signaling 6 L homeolog antikoerper, suppressor of cytokine signaling antikoerper, suppressor of cytokine signaling 6b antikoerper, SOCS6 antikoerper, Socs6 antikoerper, socs6.L antikoerper, socs6 antikoerper, socs6b antikoerper

Hintergrund:

Synonyms: CIS-4, CIS4, Cish4, Cytokine inducible SH2 protein 4, Cytokine-inducible SH2 protein 4, HSPC060, SOCS-4, SOCS-6, SOCS4, Socs6, SOCS6_HUMAN, SSI4, STAI4, STAT induced STAT inhibitor 4, STAT4, STATI4, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 6.

Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008].

Gen-ID: 9306

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis