SOCS6 Antikörper (AA 1-210)

Produktnummer ABIN6148273

Produktdetails anti-SOCS6 Antikörper

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Bindungsspezifität: AA 1-210

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGED EKGGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR PIRSTSLRSH HYSPAPWPLR PTNSEETCIK MEVRVKALVH SSSPSPALNG VRKDFHDLQS ETTCQEQANS LKSSASHNGD LHLHLDEHVP

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SOCS6 (NP_004223.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6 (SOCS6 Produkte)

Synonyme: CIS-4 antikoerper, CIS4 antikoerper, HSPC060 antikoerper, SOCS-4 antikoerper, SOCS-6 antikoerper, SOCS4 antikoerper, SSI4 antikoerper, STAI4 antikoerper, STATI4 antikoerper, socs6 antikoerper, MGC81477 antikoerper, SOCS6 antikoerper, 1500012M23Rik antikoerper, 5830401B18Rik antikoerper, AI447482 antikoerper, Cis4 antikoerper, Cish4 antikoerper, Socs4 antikoerper, socs6l antikoerper, zgc:64107 antikoerper, wu:fb77f06 antikoerper, suppressor of cytokine signaling 6 antikoerper, suppressor of cytokine signaling 6 L homeolog antikoerper, suppressor of cytokine signaling antikoerper, suppressor of cytokine signaling 6b antikoerper, SOCS6 antikoerper, Socs6 antikoerper, socs6.L antikoerper, socs6 antikoerper, socs6b antikoerper

Hintergrund: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.,SOCS6,CIS-4,CIS4,HSPC060,SOCS-4,SOCS-6,SOCS4,SSI4,STAI4,STATI4,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,SOCS6

Molekulargewicht: 59 kDa

Gen-ID: 9306

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis