Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD25 Antikörper

IL2RA Reaktivität: Human FACS, IF, Func Wirt: Maus Monoclonal IL2RA-423 unconjugated
Produktnummer ABIN6934024
  • Target Alle CD25 (IL2RA) Antikörper anzeigen
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Reaktivität
    • 192
    • 131
    • 36
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 151
    • 97
    • 85
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 254
    • 79
    • 2
    Monoklonal
    Konjugat
    • 114
    • 35
    • 30
    • 28
    • 24
    • 16
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD25 Antikörper ist unkonjugiert
    Applikation
    • 229
    • 91
    • 59
    • 52
    • 44
    • 43
    • 22
    • 17
    • 14
    • 14
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Spezifität
    Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human IL2RA protein
    Klon
    IL2RA-423
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product IL2RA Primärantikörper
  • Applikationshinweise

    Positive Control: PHA-stimulated human lymphocytes. Human lymph nodes and tonsils.

    Known Application: Functional Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Andere Bezeichnung
    IL2RA (IL2RA Produkte)
    Synonyme
    CD25 antikoerper, IDDM10 antikoerper, IL2R antikoerper, TCGFR antikoerper, IL2RAC antikoerper, IL-2RA antikoerper, Il2r antikoerper, Ly-43 antikoerper, interleukin 2 receptor subunit alpha antikoerper, interleukin-2 receptor subunit alpha-like antikoerper, interleukin 2 receptor, alpha chain antikoerper, IL2RA antikoerper, Il2ra antikoerper, LOC100222957 antikoerper
    Molekulargewicht
    55kDa
    Gen-ID
    3559
    UniProt
    P01589
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
Sie sind hier:
Kundenservice