CD25 Antikörper
Kurzübersicht für CD25 Antikörper (ABIN7074349)
Target
Alle CD25 (IL2RA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse IL2RA
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Applikationshinweise
- WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:200-1:1000/1:250-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Andere Bezeichnung
- IL-2 Receptor alpha
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Hintergrund
- IL-2Rα(Activated T cells IL-2Rα Chain 55), also kown as membrane interleukin-2 receptor (mIL-2R) or CD25, is a protein encoded by IL2RA gene in Human. This protein is 55 kDa which is the high affinity composition of IL-2R. Few IL-2α chains will express in inactive T cells, while the expression will remarkably increase followed by IL-2 accumulation, when T cell surface receptor (TCR) is active. IL-2αchains will become soluble interleukin-2 receptor (sIL-2R) when they are detached from cell membrane into serum, and the molecular weight of sIL-2R is 45 kDa. The concentration of sIL-2R in serum can be used for a mark to measure T cells activation and IL-2Rα chains expression.
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Molekulargewicht
- 45 kDa
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Gen-ID
- 16184
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NCBI Accession
- NP_032393
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UniProt
- P01590
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Pathways
- JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
Target
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