STAT1 Antikörper (AA 2-230)
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- Target Alle STAT1 Antikörper anzeigen
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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Bindungsspezifität
- AA 2-230
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Reaktivität
- Human, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser STAT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- Mouse IgG monoclonal antibody for STAT1 detection. Tested with WB, IHC-P, ICC/IF, FCM in Human,Monkey.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Mouse IgG monoclonal antibody for STAT1 detection. Tested with WB, IHC-P, ICC/IF, FCM in Human,Monkey.
- Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human STAT1 recombinant protein (Position: S2-A230). Human STAT1 shares 91.2% amino acid (aa) sequence identity with mouse STAT1.
- Klon
- 12C7
- Isotyp
- IgG
- Top Product
- Discover our top product STAT1 Primärantikörper
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- Applikationshinweise
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Immunocytochemistry/Immunofluorescence|2 μg/mL Flow Cytometry|1-3 μg/1x106 cells
- Kommentare
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Andere Bezeichnung
- STAT1 (STAT1 Produkte)
- Synonyme
- CANDF7 antikoerper, ISGF-3 antikoerper, STAT91 antikoerper, 2010005J02Rik antikoerper, AA408197 antikoerper, XStat1 antikoerper, STAT4 antikoerper, DD6G4-4 antikoerper, STAT antikoerper, STAT1 antikoerper, dZ182H3.3 antikoerper, si:by134g18.2 antikoerper, si:by51f19.1 antikoerper, si:dz182h3.3 antikoerper, si:dz199m19.1 antikoerper, si:dz73o4.2 antikoerper, stat1 antikoerper, signal transducer and activator of transcription 1 antikoerper, signal transducer and activator of transcription 1 L homeolog antikoerper, signal transducer and activator of transcription 1, 91kDa antikoerper, signal transducer and activator of transcription 4 antikoerper, signal transducer and activator of transcription 1a antikoerper, STAT1 antikoerper, Stat1 antikoerper, stat1.L antikoerper, stat4 antikoerper, stat1a antikoerper
- Hintergrund
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Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1
Background: Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
- Gen-ID
- 6772
- UniProt
- P42224
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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