IDH2 Antikörper

Produktnummer ABIN6570980

Produktdetails anti-IDH2 Antikörper

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human IDH2 (NP_002159.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:20-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IDH2

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Andere Bezeichnung: IDH2 (IDH2 Produkte)

Synonyme: F6P23.14 antikoerper, F6P23_14 antikoerper, IDH-II antikoerper, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 antikoerper, isocitrate dehydrogenase II antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, D2HGA2 antikoerper, ICD-M antikoerper, IDH antikoerper, IDHM antikoerper, IDP antikoerper, IDPM antikoerper, mNADP-IDH antikoerper, E430004F23 antikoerper, IDPm antikoerper, Idh-2 antikoerper, wu:fb33c06 antikoerper, wu:fk31e05 antikoerper, wu:fq43b01 antikoerper, zgc:55485 antikoerper, idh2 antikoerper, IDH2 antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog antikoerper, isocitrate dehydrogenase [NADP], mitochondrial antikoerper, IDH2 antikoerper, Idh2 antikoerper, idh2.S antikoerper, idh2 antikoerper, LOC100441867 antikoerper

Hintergrund: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 51kDa

Calculated_MW: 45kDa/50kDa

Gen-ID: 3418

UniProt: P48735

Pathways: Warburg Effekt