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IDH2 Antikörper (C-Term)

IDH2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043856
  • Target Alle IDH2 Antikörper anzeigen
    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
    Bindungsspezifität
    • 16
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 413-447, C-Term
    Reaktivität
    • 55
    • 39
    • 35
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 47
    • 7
    • 1
    Kaninchen
    Klonalität
    • 39
    • 16
    Polyklonal
    Konjugat
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IDH2 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 19
    • 16
    • 13
    • 13
    • 11
    • 11
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Isocitrate dehydrogenase [NADP], mitochondrial(IDH2) detection. Tested with WB, IHC-P in Human, Mouse,Rat.
    Sequenz
    KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Isocitrate dehydrogenase [NADP], mitochondrial(IDH2) detection. Tested with WB, IHC-P in Human, Mouse,Rat.
    Gene Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
    Protein Name: Isocitrate dehydrogenase [NADP], mitochondrial
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2 (413-447aa KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR), identical to the related mouse and rat sequences.
    Isotyp
    IgG
    Top Product
    Discover our top product IDH2 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
    Andere Bezeichnung
    IDH2 (IDH2 Produkte)
    Synonyme
    F6P23.14 antikoerper, F6P23_14 antikoerper, IDH-II antikoerper, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 antikoerper, isocitrate dehydrogenase II antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, D2HGA2 antikoerper, ICD-M antikoerper, IDH antikoerper, IDHM antikoerper, IDP antikoerper, IDPM antikoerper, mNADP-IDH antikoerper, E430004F23 antikoerper, IDPm antikoerper, Idh-2 antikoerper, wu:fb33c06 antikoerper, wu:fk31e05 antikoerper, wu:fq43b01 antikoerper, zgc:55485 antikoerper, idh2 antikoerper, IDH2 antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog antikoerper, isocitrate dehydrogenase [NADP], mitochondrial antikoerper, IDH2 antikoerper, Idh2 antikoerper, idh2.S antikoerper, idh2 antikoerper, LOC100441867 antikoerper
    Hintergrund
    Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

    Synonyms: D2HGA2 antibody|ICD-M antibody|IDH antibody|IDH2 antibody|IDHM antibody|IDHP_HUMAN antibody|IDP antibody|IDPM antibody|Isocitrate dehydrogenase [NADP], mitochondrial antibody|Isocitrate dehydrogenase 2 (NADP+), mitochondrial antibody|mNADP-IDH antibody|NADP(+)-specific ICDH antibody|Oxalosuccinate decarboxylase antibody
    Gen-ID
    3418
    UniProt
    P48735
    Pathways
    Warburg Effekt
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