GRB2 Antikörper

Produktnummer ABIN645847

Produktdetails anti-GRB2 Antikörper

Target: GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Ziege

Konjugat: Dieser GRB2 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Spezifität: The Goat Anti-GRB2 antibody detects protein derived from human recombinant protein and Jurkat kysate at various concentrations.

Kreuzreaktivität: Human, Maus, Ratte (Rattus), Hund, Zebrafisch (Danio rerio)

Produktmerkmale: Goat Anti-GRB2

Immunogen: Peptide with sequence C-PRNYVTPVNRNV, from the C Terminus of the protein sequence according to NP_002077.1, NP_987102.1, was used as an immunogen.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Lagerung: -20 °C

Details zu GRB2

Target: GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

Andere Bezeichnung: GRB2 (GRB2 Produkte)

Synonyme: GRB2 antikoerper, grb2 antikoerper, AA408164 antikoerper, Ash antikoerper, ASH antikoerper, EGFRBP-GRB2 antikoerper, Grb3-3 antikoerper, MST084 antikoerper, MSTP084 antikoerper, NCKAP2 antikoerper, wu:fb18e12 antikoerper, wu:fb34e06 antikoerper, zgc:73077 antikoerper, growth factor receptor bound protein 2 antikoerper, growth factor receptor-bound protein 2 antikoerper, growth factor receptor-bound protein 2b antikoerper, GRB2 antikoerper, grb2 antikoerper, Grb2 antikoerper, grb2b antikoerper

Hintergrund: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_002077

Pathways: RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation