GRB2 Produkte
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Kategorien
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte GRB2 Kategorien
GRB2 Antikörper
High quality antibodies with extensive validation data.
GRB2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRB2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GRB2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Chicken, Dog, Human, Mouse, Rat
Applikation
ELISA, IHC (p)
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN686932
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), IF, ICC
Validierungen
- (9)
Kat. Nr.
ABIN2854697
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF
Validierungen
- (6)
Kat. Nr.
ABIN7267518
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GRB2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6956336
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967248
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380816
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene GRB2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355702
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355704
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3122684
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GRB2 Produkten
: "Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, Issue 2, pp. 120-131, (2017) (PubMed).: "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." in: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).
: "Recruitment of the adaptor protein Grb2 to EGFR tetramers." in: Biochemistry, Vol. 53, Issue 16, pp. 2594-604, (2014) (PubMed).
: "An analysis of the phosphoproteome of immune cell lines exposed to the immunomodulatory mycotoxin deoxynivalenol." in: Biochimica et biophysica acta, Vol. 1814, Issue 7, pp. 850-7, (2011) (PubMed).
: "The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts." in: Molecular and cellular biology, Vol. 30, Issue 18, pp. 4492-506, (2010) (PubMed).
: "Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation." in: Molecular biology of the cell, Vol. 21, Issue 9, pp. 1597-608, (2010) (PubMed).
: "Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1428-36, (2008) (PubMed).
: "Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction." in: Cellular signalling, Vol. 19, Issue 11, pp. 2277-85, (2007) (PubMed).
: "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 46, pp. 18013-8, (2007) (PubMed).
: "Angiotensin II type 2 receptor-dependent increases in nitric oxide synthase expression in the pulmonary endothelium is mediated via a G alpha i3/Ras/Raf/MAPK pathway." in: American journal of physiology. Cell physiology, Vol. 292, Issue 6, pp. C2185-96, (2007) (PubMed).
Synonyme und alternative Namen zu GRB2
growth factor receptor bound protein 2 (GRB2), growth factor receptor-bound protein 2 (grb2), growth factor receptor bound protein 2 (Grb2), growth factor receptor-bound protein 2b (grb2b), AA408164, Ash, ASH, EGFRBP-GRB2, GRB2, grb2, Grb3-3, MST084, MSTP084, NCKAP2, wu:fb18e12, wu:fb34e06, zgc:73077Bezeichner auf Proteinebene für GRB2
- growth factor receptor-bound protein 2
- Growth factor receptor-bound protein 2
- SH2/SH3 adapter GRB2
- adapter protein GRB2
- protein Ash
- HT027
- abundant SRC homology
- epidermal growth factor receptor-binding protein GRB2
- growth factor receptor-bound protein 3
- growth factor receptor bound protein 2
- fb18e12
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