GRIA2 Produkte
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Kategorien
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG\; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte GRIA2 Kategorien
GRIA2 Antikörper
High quality antibodies with extensive validation data.
GRIA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRIA2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GRIA2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN969524
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7267414
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC, Neut
Validierungen
- (5)
Kat. Nr.
ABIN5611163
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene GRIA2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956147
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956148
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380591
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene GRIA2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3080937
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3133383
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3092808
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GRIA2 Produkten
: "Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 95, (2022) (PubMed).: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).
: "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 763-775, (2018) (PubMed).
: "Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis." in: Scientific reports, Vol. 8, Issue 1, pp. 12856, (2018) (PubMed).
: "The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat." in: Behavioural brain research, Vol. 332, pp. 99-109, (2017) (PubMed).
: "Cell-free methods to produce structurally intact mammalian membrane proteins." in: Scientific reports, Vol. 6, pp. 30442, (2016) (PubMed).
: "Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development." in: Scientific reports, Vol. 6, pp. 35456, (2016) (PubMed).
: "Disrupting GluA2-GAPDH Interaction Affects Axon and Dendrite Development." in: Scientific reports, Vol. 6, pp. 30458, (2016) (PubMed).
: "Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo." in: Brain structure & function, Vol. 220, Issue 1, pp. 47-58, (2015) (PubMed).
: "TRPC3 channels critically regulate hippocampal excitability and contextual fear memory." in: Behavioural brain research, Vol. 281, pp. 69-77, (2015) (PubMed).
Synonyme und alternative Namen zu GRIA2
glutamate ionotropic receptor AMPA type subunit 2 (GRIA2), glutamate receptor, ionotropic, AMPA 2 (GRIA2), glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2), glutamate ionotropic receptor AMPA type subunit 2 (Gria2), glutamate receptor, ionotropic, AMPA 2a (gria2a), glutamate receptor, ionotropic, AMPA 2 S homeolog (gria2.S), GluA2, GluR-2, Glur-2, GluR-B, gluR-B, GluR-K2, GLUR2, Glur2, GluR2, glur2, glur2a, GLURB, gria2.1, HBGR2, zfGRIA2[a]Bezeichner auf Proteinebene für GRIA2
- AMPA-selective glutamate receptor 2
- gluR-2
- gluR-B
- glutamate receptor 2
- Glutamate receptor 2
- gluR-K2
- glutamate receptor ionotropic, AMPA 2
- AMPA selective glutamate receptor
- glutamate receptor B
- glutamate receptor, ionotropic, AMPA 2.1
- AMPA glutamate receptor 2
- AMPA receptor GluR2/B
- glutamate receptor AMPA 2
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