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14-3-3 sigma/SFN Antikörper (Middle Region)

SFN Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN634143

Datenblatt (PDF)

Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen

14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
Bindungsspezifität
15

13

11

9

7

7

7

6

6

3

3

2

2

2

1

1

1

1

1

1
Middle Region
Reaktivität
103

35

28

5

5

5

4

4

4

4

3

1

1

1

1

1
Human, Maus, Ratte
Wirt
93

9

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
88

17
Polyklonal
Konjugat
48

11

9

6

4

4

3

3

3

3

3

3

1

1

1

1

1
Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
Applikation
86

44

38

23

17

15

14

13

13

9

3

2

1

1

1

1

1

1
Western Blotting (WB)

Spezifität

SFN antibody was raised against the middle region of SFN

Aufreinigung

Affinity purified

Immunogen

SFN antibody was raised using the middle region of SFN corresponding to a region with amino acids FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLT

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Applikationshinweise

WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare

SFN Blocking Peptide, catalog no. 33R-2923, is also available for use as a blocking control in assays to test for specificity of this SFN antibody

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SFN antibody in PBS

Konzentration

Lot specific

Buffer

PBS

Handhabung

Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
Target

14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Andere Bezeichnung

SFN (SFN Produkte)

Synonyme

YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper

Hintergrund

SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

Molekulargewicht

28 kDa (MW of target protein)

Pathways

p53 Signalweg, Myometrial Relaxation and Contraction