14-3-3 sigma/SFN Antikörper (AA 140-156)
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- Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Bindungsspezifität
- AA 140-156
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Aufreinigung
- Antigen affinity
- Immunogen
- Amino acids 140-156 (KKRIIDSARSAYQEAMD) were used as the immunogen for this 14-3-3 sigma antibody (100% homologous in human, mouse and rat).
- Isotyp
- IgG
- Top Product
- Discover our top product SFN Primärantikörper
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anti-Stratifin (SFN) antibody
SFN Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (C-Term) antibodySFN Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, ELISA, IHC (p), IP Wirt: Maus Monoclonal 3C3 unconjugated
anti-Stratifin (SFN) (Internal Region) antibodyVerified SFN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (AA 222-248), (C-Term) antibodySFN Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB27523 unconjugated
anti-Stratifin (SFN) antibodySFN Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal CPTC-SFN-2 unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2G2 unconjugated
anti-Stratifin (SFN) (AA 1-249) antibodySFN Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 3C3 unconjugated
anti-Stratifin (SFN) (AA 140-156), (Middle Region) antibodySFN Reaktivität: Human WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the 14-3-3 sigma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the 14-3-3 sigma antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Andere Bezeichnung
- 14-3-3 sigma (SFN Produkte)
- Synonyme
- YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper
- Hintergrund
- Stratifin (SFN), also known as 14-3-3 sigma, is strongly induced by gamma irradiation and other DNA-damaging agents. The induction of 14-3-3-sigma is mediated by a p53 -responsive element located 1.8 kb upstream of its transcription start site. Leffers et al.(1993) obtained a peptide sequence and subsequently cloned a T-cell cDNA of the 14-3-3 family of conserved proteins. The protein called stratifin was shown to be diffusely distributed in the cytoplasm and was present in cultured epithelial cells. It was most abundant in tissues enriched in stratified keratinizing epithelium.
- UniProt
- P31947
- Pathways
- p53 Signalweg, Myometrial Relaxation and Contraction
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