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14-3-3 sigma/SFN Antikörper (C-Term)

SFN Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854692
  • Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Bindungsspezifität
    • 15
    • 13
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 104
    • 35
    • 28
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 94
    • 9
    • 2
    • 1
    Kaninchen
    Klonalität
    • 89
    • 17
    Polyklonal
    Konjugat
    • 47
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
    Applikation
    • 75
    • 44
    • 39
    • 23
    • 16
    • 15
    • 14
    • 14
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to 14-3-3 sigma (stratifin)
    14-3-3 sigma antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 14-3-3 sigma. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , GL261 , PC-12 , A549

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Andere Bezeichnung
    stratifin (SFN Produkte)
    Synonyme
    YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper
    Hintergrund
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. p53-regulated inhibitor of G2/M progression.

    Cellular Localization: Cytoplasm , Nucleus , Secreted
    Molekulargewicht
    28 kDa
    Gen-ID
    2810
    UniProt
    P31947
    Pathways
    p53 Signalweg, Myometrial Relaxation and Contraction
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