14-3-3 sigma/SFN Antikörper
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- Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human full-length SFN protein
- Klon
- CPTC-SFN-2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product SFN Primärantikörper
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anti-Stratifin (SFN) antibody
SFN Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (C-Term) antibodySFN Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, ELISA, IHC (p), IP Wirt: Maus Monoclonal 3C3 unconjugated
anti-Stratifin (SFN) (Internal Region) antibodyVerified SFN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Stratifin (SFN) (AA 140-156) antibodySFN Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stratifin (SFN) (AA 222-248), (C-Term) antibodySFN Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB27523 unconjugated
anti-Stratifin (SFN) (AA 1-248) antibodySFN Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2G2 unconjugated
anti-Stratifin (SFN) (AA 1-249) antibodySFN Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 3C3 unconjugated
anti-Stratifin (SFN) (AA 140-156), (Middle Region) antibodySFN Reaktivität: Human WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Positive Control: PC-3 cells, Skin and tissues enriched in stratified squamous keratinizing epithelium. HaCaT, hTCEpi, A-431 cell lines.
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Andere Bezeichnung
- SFN (SFN Produkte)
- Synonyme
- YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper
- Hintergrund
- SFN (stratifin) is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
- Molekulargewicht
- 28kDa
- Gen-ID
- 2810
- UniProt
- P31947
- Pathways
- p53 Signalweg, Myometrial Relaxation and Contraction
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