Indian Hedgehog Antikörper
Kurzübersicht für Indian Hedgehog Antikörper (ABIN630306)
Target
Alle Indian Hedgehog (IHH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified
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Immunogen
- IHH antibody was raised using a synthetic peptide corresponding to a region with amino acids AAWGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIAR
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Applikationshinweise
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WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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IHH Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this IHH antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IHH antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Indian Hedgehog (IHH)
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Andere Bezeichnung
- IHH
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Hintergrund
- IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
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Molekulargewicht
- 45 kDa (MW of target protein)
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Pathways
- Hedgehog Signalweg
Target
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