Indian Hedgehog Antikörper (N-Term)

Produktnummer ABIN2782160

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-Indian Hedgehog Antikörper (ABIN2782160) detektiert spezifisch Indian Hedgehog in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für Indian Hedgehog Antikörper (N-Term) (ABIN2782160)

Target: Indian Hedgehog (IHH)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Indian Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Indian Hedgehog Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IHH Antibody - N-terminal region

Sequenz: AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR

Homologie: Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IHH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103013

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Indian Hedgehog Antikörper (ABIN2782160)

Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

Details zu Indian Hedgehog

Target: Indian Hedgehog (IHH)

Andere Bezeichnung: IHH

Hintergrund:

Background Information: IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).

Gene Name: Indian hedgehog

Alternative Symbols: BDA1, HHG2

Protein Name: Indian hedgehog protein

Molekulargewicht: 45 kDa

Gen-ID: 3549

NCBI Accession: NP_002172

UniProt: Q14623

Pathways: Hedgehog Signalweg