DR4 Antikörper
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- Target Alle DR4 Antikörper anzeigen
- DR4 (Drought-Repressed 4 Protein (DR4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DR4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- TR10A antibody detects endogenous levels of total TR10A
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TR10A
- Isotyp
- IgG
- Top Product
- Discover our top product DR4 Primärantikörper
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- Applikationshinweise
- WB: 1:500~1:3000, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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- Target
- DR4 (Drought-Repressed 4 Protein (DR4))
- Andere Bezeichnung
- TR10A (DR4 Produkte)
- Synonyme
- APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNF receptor superfamily member 10a antikoerper, TNFRSF10A antikoerper
- Hintergrund
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Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Gene: TNFRSF10A
- Molekulargewicht
- 50kDa
- Gen-ID
- 8797
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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