DR4 Antikörper (AA 401-450)

Produktnummer ABIN1533474

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DR4 in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Affe.

Kurzübersicht für DR4 Antikörper (AA 401-450) (ABIN1533474)

Target: DR4 (Drought-Repressed 4 Protein (DR4))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-DR4 Antikörper

Bindungsspezifität: AA 401-450

Verwendungszweck: DR4 Antibody

Spezifität: DR4 Polyclonal Antibody detects endogenous levels of DR4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TNFRSF10A. AA range:401-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DR4

Target: DR4 (Drought-Repressed 4 Protein (DR4))

Andere Bezeichnung: TR10A

Hintergrund:

Synonyms: TNFRSF10A, APO2, DR4, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD antigen CD261

Background: The protein encoded byThis gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008],

Gene Name: TNFRSF10A

Protein Name: Tumor necrosis factor receptor superfamily member 10A

Molekulargewicht: 50 kDa

Gen-ID: 8797

OMIM: 603611

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity