DR4 Antikörper (AA 401-468)
Kurzübersicht für DR4 Antikörper (AA 401-468) (ABIN670581)
Target
Alle DR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 401-468
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Verwendungszweck
- TNFRSF10A Polyclonal Antibody
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DR4
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000),
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- DR4 (Drought-Repressed 4 Protein (DR4))
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Andere Bezeichnung
- DR4
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Hintergrund
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Synonyms: DR4, APO2, CD261, TRAILR1, TRAILR-1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, TNFRSF10A
Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
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Gen-ID
- 8797
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UniProt
- O00220
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Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
Target
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