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DR4 Antikörper (AA 401-468)

DR4 Reaktivität: Human, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN670581
  • Target Alle DR4 Antikörper anzeigen
    DR4 (Drought-Repressed 4 Protein (DR4))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-468
    Reaktivität
    • 33
    • 16
    • 10
    • 2
    Human, Ratte
    Wirt
    • 28
    • 5
    Kaninchen
    Klonalität
    • 28
    • 5
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DR4 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DR4
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DR4 (Drought-Repressed 4 Protein (DR4))
    Andere Bezeichnung
    DR4 (DR4 Produkte)
    Synonyme
    APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNF receptor superfamily member 10a antikoerper, TNFRSF10A antikoerper
    Hintergrund

    Synonyms: DR4, APO2, CD261, TRAILR1, TRAILR-1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, TNFRSF10A

    Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

    Gen-ID
    8797
    UniProt
    O00220
    Pathways
    Apoptose, Positive Regulation of Endopeptidase Activity
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