TAF1 Antikörper (Internal Region)
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- Target Alle TAF1 Antikörper anzeigen
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TAF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- TAF1 Antibody detects endogenous levels of total TAF1.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TAF1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TAF1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
- Andere Bezeichnung
- TAF1 (TAF1 Produkte)
- Synonyme
- BG:DS00004.13 antikoerper, CG17603 antikoerper, Dmel\\CG17603 antikoerper, EfW1 antikoerper, SR3-5 antikoerper, TAF antikoerper, TAF1 antikoerper, TAF200 antikoerper, TAF230 antikoerper, TAF250 antikoerper, TAF250/230 antikoerper, TAFII-250 antikoerper, TAFII250 antikoerper, TAF[II]250 antikoerper, TAF[[II]] antikoerper, TAF[[II]]230 antikoerper, TAF[[II]]250 antikoerper, TAF[[II]]250/230 antikoerper, TFIID antikoerper, TFIID TAF250 antikoerper, Taf1p antikoerper, Taf200 antikoerper, Taf230 antikoerper, Taf250 antikoerper, Taf[[II]]250 antikoerper, cel antikoerper, cell antikoerper, d230 antikoerper, dTAF230 antikoerper, dTAF250 antikoerper, dTAFII250 antikoerper, dTAF[[II]]230 antikoerper, dTAF[[II]]250 antikoerper, dmTAF1 antikoerper, dmTAF[[II]]230 antikoerper, l(3)84Ab antikoerper, p230 antikoerper, 250kDa antikoerper, AU015687 antikoerper, B430306D02Rik antikoerper, Ccg-1 antikoerper, Ccg1 antikoerper, KAT4 antikoerper, N-TAF1 antikoerper, Taf2a antikoerper, RGD1562050 antikoerper, BA2R antikoerper, CCG1 antikoerper, CCGS antikoerper, DYT3 antikoerper, DYT3/TAF1 antikoerper, NSCL2 antikoerper, OF antikoerper, P250 antikoerper, TAF2A antikoerper, XDP antikoerper, TAF(II)250 antikoerper, p250 antikoerper, TBP-associated factor 1 antikoerper, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antikoerper, transcription initiation factor TFIID subunit 1 antikoerper, transcription initiation factor TFIID, subunit TAF1 antikoerper, TATA-box binding protein associated factor 1 antikoerper, Taf1 antikoerper, TAF1 antikoerper, LOC5567420 antikoerper, CpipJ_CPIJ003658 antikoerper, TAF11.1 antikoerper, HAF1501 antikoerper, HAF1502 antikoerper, LOC100457071 antikoerper
- Hintergrund
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Description: Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:25412659, PubMed:27007846). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity (PubMed:25412659). Essential for progression of the G1 phase of the cell cycle (PubMed:11278496, PubMed:15053879, PubMed:2038334, PubMed:8450888, PubMed:8625415, PubMed:9660973, PubMed:9858607). Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300).
Gene: TAF1
- Molekulargewicht
- 212kDa
- Gen-ID
- 6872
- UniProt
- P21675
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