TAF1 Produkte
(TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
Kategorien
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.[provided by RefSeq, Aug 2009].
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Ausgewählte TAF1 Kategorien
TAF1 Antikörper
High quality antibodies with extensive validation data.
TAF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TAF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TAF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN233826
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, ChIP
Validierungen
- (4)
Kat. Nr.
ABIN2779667
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN563083
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene TAF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5594421
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1162526
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TAF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125310
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125311
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125309
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TAF1 Produkten
: "The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells." in: Molecular and cellular biology, Vol. 32, Issue 10, pp. 1984-97, (2012) (PubMed).: "Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression." in: Molecular cell, Vol. 13, Issue 6, pp. 867-78, (2004) (PubMed).
: "Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 15886-92, (2001) (PubMed).
: "Structure and function of a human TAFII250 double bromodomain module." in: Science (New York, N.Y.), Vol. 288, Issue 5470, pp. 1422-5, (2000) (PubMed).
Synonyme und alternative Namen zu TAF1
TBP-associated factor 1 (Taf1), TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (TAF1), transcription initiation factor TFIID subunit 1 (LOC5567420), transcription initiation factor TFIID subunit 1 (CpipJ_CPIJ003658), transcription initiation factor TFIID subunit 1 (TAF11.1), transcription initiation factor TFIID, subunit TAF1 (HAF1501), transcription initiation factor TFIID, subunit TAF1 (HAF1502), TATA-box binding protein associated factor 1 (TAF1), transcription initiation factor TFIID subunit 1 (LOC100457071), TATA-box binding protein associated factor 1 (Taf1), 250kDa, AU015687, B430306D02Rik, BA2R, BG:DS00004.13, Ccg-1, Ccg1, CCG1, CCGS, cel, cell, CG17603, d230, Dmel\\CG17603, dmTAF1, dmTAF[[II]]230, dTAF230, dTAF250, dTAFII250, dTAF[[II]]230, dTAF[[II]]250, DYT3, DYT3/TAF1, EfW1, KAT4, l(3)84Ab, N-TAF1, NSCL2, OF, p230, P250, p250, RGD1562050, SR3-5, TAF, TAF(II)250, TAF1, Taf1p, Taf2a, TAF2A, TAF200, Taf200, TAF230, Taf230, TAF250, Taf250, TAF250/230, TAFII-250, TAFII250, TAF[II]250, TAF[[II]], TAF[[II]]230, TAF[[II]]250, Taf[[II]]250, TAF[[II]]250/230, TFIID, TFIID TAF250, XDPBezeichner auf Proteinebene für TAF1
- CG17603-PA
- CG17603-PB
- CG17603-PC
- CG17603-PD
- CG17603-PE
- TATA-associated factor 250
- TBP-associated factor
- TBP-associated factor 250
- TBP-associated factor 250kD
- TFIID 230 kda subunit
- Taf1-PA
- Taf1-PB
- Taf1-PC
- Taf1-PD
- Taf1-PE
- cell lethal
- suppressor of Ras85D 3-5
- TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
- transcription initiation factor TFIID subunit 1
- transcription initiation factor TFIID, subunit TAF1
- TBP-associated factor 1-like
- transcription initiation factor TFIID subunit 1-like
- TAF(II)250
- TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform
- TAFII-250
- TBP-associated factor 250 kDa
- cell cycle gene 1 protein
- cell cycle, G1 phase defect
- p250
- transcription initiation factor TFIID 250 kDa subunit
- complementation of cell cycle block, G1-to-S
- transcription factor TFIID p250 polypeptide
- Cell cycle gene 1 protein
- Transcription initiation factor TFIID 250 kDa subunit
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