TAF1 Antikörper (C-Term)

Produktnummer ABIN2779667

Produktdetails anti-TAF1 Antikörper

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Sequenz: YEVSEEEEDE EEEEQRSGPS VLSQVHLSED EEDSEDFHSI AGDSDLDSDE

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TAF1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TAF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1872 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TAF1

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Andere Bezeichnung: TAF1 (TAF1 Produkte)

Synonyme: BG:DS00004.13 antikoerper, CG17603 antikoerper, Dmel\\CG17603 antikoerper, EfW1 antikoerper, SR3-5 antikoerper, TAF antikoerper, TAF1 antikoerper, TAF200 antikoerper, TAF230 antikoerper, TAF250 antikoerper, TAF250/230 antikoerper, TAFII-250 antikoerper, TAFII250 antikoerper, TAF[II]250 antikoerper, TAF[[II]] antikoerper, TAF[[II]]230 antikoerper, TAF[[II]]250 antikoerper, TAF[[II]]250/230 antikoerper, TFIID antikoerper, TFIID TAF250 antikoerper, Taf1p antikoerper, Taf200 antikoerper, Taf230 antikoerper, Taf250 antikoerper, Taf[[II]]250 antikoerper, cel antikoerper, cell antikoerper, d230 antikoerper, dTAF230 antikoerper, dTAF250 antikoerper, dTAFII250 antikoerper, dTAF[[II]]230 antikoerper, dTAF[[II]]250 antikoerper, dmTAF1 antikoerper, dmTAF[[II]]230 antikoerper, l(3)84Ab antikoerper, p230 antikoerper, 250kDa antikoerper, AU015687 antikoerper, B430306D02Rik antikoerper, Ccg-1 antikoerper, Ccg1 antikoerper, KAT4 antikoerper, N-TAF1 antikoerper, Taf2a antikoerper, RGD1562050 antikoerper, BA2R antikoerper, CCG1 antikoerper, CCGS antikoerper, DYT3 antikoerper, DYT3/TAF1 antikoerper, NSCL2 antikoerper, OF antikoerper, P250 antikoerper, TAF2A antikoerper, XDP antikoerper, TAF(II)250 antikoerper, p250 antikoerper, TBP-associated factor 1 antikoerper, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antikoerper, transcription initiation factor TFIID subunit 1 antikoerper, transcription initiation factor TFIID, subunit TAF1 antikoerper, TATA-box binding protein associated factor 1 antikoerper, Taf1 antikoerper, TAF1 antikoerper, LOC5567420 antikoerper, CpipJ_CPIJ003658 antikoerper, TAF11.1 antikoerper, HAF1501 antikoerper, HAF1502 antikoerper, LOC100457071 antikoerper

Hintergrund: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF1 encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Two transcripts encoding different isoforms have been identified for this gene.
Alias Symbols: BA2R, CCG1, CCGS, DYT3, KAT4, NSCL2, OF, P250, TAF2A, TAFII250, XDP, N-TAF1, DYT3/TAF1
Protein Interaction Partner: AR, UBE2I, TAF4B, HIST3H3, UBC, TBP, MED26, TAF3, TAF9B, TAF7, TAF6, TAF5, TAF4, TAF2, CCNT1, GFI1B, TP53, MEN1, GTF2F1, BRMS1, PHF8, PAX3, CTCF, HIST1H4A, HIST1H3A, TAF8, MDM2, ASF1A, SIN3A, ALL1, SMARCA2, APC, RANBP2, MAX, TBPL1, TAF13, TAF10, ASF1B, TA
Protein Size: 1872

Molekulargewicht: 215 kDa

Gen-ID: 6872

NCBI Accession: NM_138923, NP_620278