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14-3-3 sigma/SFN Antikörper (Internal Region)

SFN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265025
  • Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Bindungsspezifität
    • 15
    • 13
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 103
    • 35
    • 28
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 93
    • 9
    • 2
    • 1
    Kaninchen
    Klonalität
    • 88
    • 17
    Polyklonal
    Konjugat
    • 48
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
    Applikation
    • 86
    • 44
    • 38
    • 23
    • 17
    • 15
    • 14
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    14-3-3 sigma Antibody detects endogenous levels of total 14-3-3 sigma.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human 14-3-3 sigma, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SFN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Andere Bezeichnung
    SFN (SFN Produkte)
    Synonyme
    YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper
    Hintergrund

    Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

    Gene: SFN

    Molekulargewicht
    28kDa
    Gen-ID
    2810
    UniProt
    P31947
    Pathways
    p53 Signalweg, Myometrial Relaxation and Contraction
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