RYK Antikörper (Internal Region)

Produktnummer ABIN6264891

Produktdetails anti-RYK Antikörper

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RYK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RYK Antibody detects endogenous levels of total RYK.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RYK, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Andere Bezeichnung: RYK (RYK Produkte)

Synonyme: RYK antikoerper, jtk5 antikoerper, ryk1 antikoerper, jtk5a antikoerper, d3s3195 antikoerper, wu:fb37b12 antikoerper, wu:fi05b06 antikoerper, zgc:158381 antikoerper, MGC114645 antikoerper, D3S3195 antikoerper, JTK5 antikoerper, JTK5A antikoerper, RYK1 antikoerper, AW536699 antikoerper, ERK-3 antikoerper, Vik antikoerper, receptor-like tyrosine kinase antikoerper, receptor-like tyrosine kinase S homeolog antikoerper, tyrosine-protein kinase RYK antikoerper, RYK antikoerper, ryk antikoerper, ryk.S antikoerper, LOC100541106 antikoerper, Ryk antikoerper

Hintergrund:

Description: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Gene: RYK

Molekulargewicht: 68 kDa

Gen-ID: 6259

UniProt: P34925

Pathways: RTK Signalweg, WNT Signalweg, Regulation of Cell Size