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RYK Produkte

(RYK Receptor-Like Tyrosine Kinase (RYK))
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].

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Ausgewählte RYK Kategorien

RYK Antikörper

High quality antibodies with extensive validation data.

RYK ELISA Kits

Reliable ELISA kits for a wide range of species.

RYK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RYK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (4)
  • (7)
Kat. Nr. ABIN392050
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7174060
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN392051
Menge 400 μL
Datenblatt Datenblatt

Empfohlene RYK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4886279
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730510
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884386
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RYK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319036
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3087682
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3121366
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RYK Produkten

Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." in: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." in: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).

Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

Synonyme und alternative Namen zu RYK

receptor-like tyrosine kinase (RYK), receptor-like tyrosine kinase (ryk), receptor-like tyrosine kinase S homeolog (ryk.S), tyrosine-protein kinase RYK (LOC100541106), receptor-like tyrosine kinase (Ryk), AW536699, d3s3195, D3S3195, ERK-3, jtk5, JTK5, jtk5a, JTK5A, MGC114645, RYK, ryk1, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381

Bezeichner auf Proteinebene für RYK

  • RYK receptor-like tyrosine kinase
  • tyrosine kinase RYK
  • ryk receptor-like tyrosine kinase
  • receptor-like tyrosine kinase
  • tyrosine-protein kinase RYK
  • tyrosine kinase-related protein
  • tyrosine-protein kinase RYK-like
  • JTK5A protein tyrosine kinase
  • hydroxyaryl-protein kinase
  • NYK-R
  • growth factor receptor
  • kinase VIK
  • met-related kinase
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