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Klotho Antikörper

KL Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262853
  • Target Alle Klotho (KL) Antikörper anzeigen
    Klotho (KL)
    Reaktivität
    • 30
    • 30
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 40
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 34
    • 13
    Polyklonal
    Konjugat
    • 29
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Klotho Antikörper ist unkonjugiert
    Applikation
    • 33
    • 22
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Klotho Antibody detects endogenous levels of total Klotho
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Klotho
    Isotyp
    IgG
    Top Product
    Discover our top product KL Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    Klotho (KL)
    Andere Bezeichnung
    Klotho (KL Produkte)
    Synonyme
    alpha-kl antikoerper, KL antikoerper, LOC100223456 antikoerper, klotho antikoerper, Klotho antikoerper, KL antikoerper, Kl antikoerper, kl antikoerper, LOC100533542 antikoerper
    Hintergrund

    Description: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).

    Gene: KL

    Molekulargewicht
    116kDa
    Gen-ID
    9365
    UniProt
    Q9UEF7
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hormone Activity, Growth Factor Binding
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