Klotho Antikörper (C-Term)

Produktnummer ABIN389493

Produktdetails anti-Klotho Antikörper

Target: Klotho (KL)

Bindungsspezifität: AA 986-1012, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Klotho Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 983~1012 amino acids from the C-terminal region of human Klotho.

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 986-1012 AA from the C-terminal region of human Klotho.

Klon: RB21226

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB = 1:1000, FACS = 1:10-50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Klotho Antikörper (ABIN389493)

Cheng, Chen, Cheng: "Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 513853, (2010) (PubMed).

Details zu Klotho

Target: Klotho (KL)

Andere Bezeichnung: Klotho (KL Produkte)

Synonyme: alpha-kl antikoerper, KL antikoerper, LOC100223456 antikoerper, klotho antikoerper, Klotho antikoerper, KL antikoerper, Kl antikoerper, kl antikoerper, LOC100533542 antikoerper

Hintergrund: Klotho is a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
Synonyms: Klotho, Klotho peptide, KL

Molekulargewicht: 116181 DA

Gen-ID: 9365

UniProt: Q9UEF7

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hormone Activity, Growth Factor Binding