Klotho Antikörper (Center)
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- Target Alle Klotho (KL) Antikörper anzeigen
- Klotho (KL)
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Klotho Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
- Spezifität
- This antibody detects Klotho at center.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 16 amino acid peptide near the center of human KLOTHO
- Top Product
- Discover our top product KL Primärantikörper
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anti-Klotho (KL) (AA 516-955) antibody
KL Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 401-500) antibodyKL Reaktivität: Human, Maus, Ratte IHC (p), IHC (fro), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 517-956) antibodyKL Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 986-1012), (C-Term) antibodyKL Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB21226 unconjugated
anti-Klotho (KL) (AA 720-769) antibodyKL Reaktivität: Human, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 251-300) antibodyKL Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Hund, Meerschweinchen, Fledermaus, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 765-981) antibodyKL Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Klotho (KL) (AA 59-508) antibodyKL Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- Klotho (KL)
- Andere Bezeichnung
- Klotho (KL Produkte)
- Synonyme
- alpha-kl antikoerper, KL antikoerper, LOC100223456 antikoerper, klotho antikoerper, Klotho antikoerper, KL antikoerper, Kl antikoerper, kl antikoerper, LOC100533542 antikoerper
- Hintergrund
- KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor. Three isoforms of KLOTHO are known to exist.Synonyms: EC 3.2.1.31, KL, Klotho
- Gen-ID
- 9365
- NCBI Accession
- NP_004786
- UniProt
- Q9UEF7
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hormone Activity, Growth Factor Binding
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