GNAQ Antikörper (Internal Region)

Produktnummer ABIN615969

Produktdetails anti-GNAQ Antikörper

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Bindungsspezifität: AA 162-175, Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GNAQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-NDLDRVADPA YLPT

Spezifität: Recognizes GNAQ / ALPHA-q (aa 162-175).

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Pig, Cow.
Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002063.2. Genename: GNAQ

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GNAQ

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Abstract: GNAQ Produkte

Synonyme: si:ch73-270f14.2 antikoerper, CMC1 antikoerper, G-ALPHA-q antikoerper, GAQ antikoerper, SWS antikoerper, Galphaq antikoerper, Gnaq antikoerper, g-alpha-q antikoerper, gaq antikoerper, gnaqb antikoerper, 1110005L02Rik antikoerper, 6230401I02Rik antikoerper, AA408290 antikoerper, AW060788 antikoerper, Dsk1 antikoerper, Dsk10 antikoerper, Gq antikoerper, GqI antikoerper, guanine nucleotide binding protein (G protein), q polypeptide antikoerper, G protein subunit alpha q antikoerper, guanine nucleotide binding protein (G protein), q polypeptide S homeolog antikoerper, guanine nucleotide binding protein, alpha q polypeptide antikoerper, gnaq antikoerper, GNAQ antikoerper, Gnaq antikoerper, gnaq.S antikoerper

Hintergrund: Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.Synonyms: GAQ, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q

Gen-ID: 2776

NCBI Accession: NP_002063

UniProt: P50148

Pathways: JAK-STAT Signalweg, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction