PLAT Antikörper (AA 23-320)
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- Target Alle PLAT Antikörper anzeigen
- PLAT (Plasminogen Activator, Tissue (PLAT))
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Bindungsspezifität
- AA 23-320
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PLAT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SQEIHARFRR GARSYQVICR DEKTQMIYQQ HQSWLRPVLR SNRVEYCWCN SGRAQCHSVP VKSCSEPRCF NGGTCQQALY FSDFVCQCPE GFAGKCCEID TRATCYEDQG ISYRGTWSTA ESGAECTNWN SSALAQKPYS GRRPDAIRLG LGNHNYCRNP DRDSKPWCYV FKAGKYSSEF CSTPACSEGN SDCYFGNGSA YRGTHSLTES GASCLPWNSM ILIGKVYTAQ NPSAQALGLG KHNYCRNPDG DAKPWCHVLK NRRLTWEYCD VPSCSTCGLR QYSQPQFRIK GGLFADIA
- Kreuzreaktivität
- Human
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 23-320 of human tPA/tPA/PLAT (NP_000921.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PLAT Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PLAT (Plasminogen Activator, Tissue (PLAT))
- Andere Bezeichnung
- PLAT (PLAT Produkte)
- Synonyme
- T-PA antikoerper, TPA antikoerper, AU020998 antikoerper, AW212668 antikoerper, D8Ertd2e antikoerper, tPA antikoerper, PATISS antikoerper, tpa antikoerper, Plat antikoerper, plat antikoerper, t-pa antikoerper, plasminogen activator, tissue type antikoerper, plasminogen activator, tissue antikoerper, chromosome 20 open reading frame 181 antikoerper, plasminogen activator, tissue L homeolog antikoerper, PLAT antikoerper, Plat antikoerper, plat antikoerper, C20orf181 antikoerper, plat.L antikoerper
- Hintergrund
- This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PLAT,T-PA,TPA,Cancer,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Cardiovascular,Blood,Serum Proteins,Hypoxia,PLAT
- Molekulargewicht
- 32 kDa/44 kDa/57 kDa/62 kDa
- Gen-ID
- 5327
- UniProt
- P00750
- Pathways
- Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom
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