PLAT Antikörper (AA 371-399)

Produktnummer ABIN390746

Produktdetails anti-PLAT Antikörper

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Bindungsspezifität: AA 371-399

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the Central region of human TPA.

Klon: RB18787

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PLAT

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Andere Bezeichnung: TPA (PLAT Produkte)

Synonyme: T-PA antikoerper, TPA antikoerper, AU020998 antikoerper, AW212668 antikoerper, D8Ertd2e antikoerper, tPA antikoerper, PATISS antikoerper, tpa antikoerper, Plat antikoerper, plat antikoerper, t-pa antikoerper, plasminogen activator, tissue type antikoerper, plasminogen activator, tissue antikoerper, chromosome 20 open reading frame 181 antikoerper, plasminogen activator, tissue L homeolog antikoerper, PLAT antikoerper, Plat antikoerper, plat antikoerper, C20orf181 antikoerper, plat.L antikoerper

Hintergrund: TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.

Molekulargewicht: 62917

Gen-ID: 5327

NCBI Accession: NP_000921, NP_127509

UniProt: P00750

Pathways: Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom