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PLAT Produkte

(Plasminogen Activator, Tissue (PLAT))

Kategorien

This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding\; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte PLAT Kategorien

PLAT Antikörper

High quality antibodies with extensive validation data.

PLAT ELISA Kits

Reliable ELISA kits for a wide range of species.

PLAT Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PLAT Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN2855635
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN1860843
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7431908
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PLAT ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN6730952
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958608
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969358
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PLAT Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2566071
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3074639
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3074638
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PLAT Produkten

Lyubenov, Shi, Zhao, Yang, Lei, Mammadova-Bach, de Chiara, Semeraro, Landini, Romagnani, Vörg, Devarapu, Welz, Kiessig, Anders: "Intravenous Glu-plasminogen attenuates cholesterol crystal embolism-induced thrombotic angiopathy, acute kidney injury and kidney infarction." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2022) (PubMed).

Shmakova, Rubina, Rysenkova, Gruzdeva, Ivashkina, Anokhin, Tkachuk, Semina: "Urokinase receptor and tissue plasminogen activator as immediate-early genes in pentylenetetrazole-induced seizures in the mouse brain." in: The European journal of neuroscience, Vol. 51, Issue 7, pp. 1559-1572, (2020) (PubMed).

Liu, Qin, Wu, Feng, Yang, Hou, Peng, Zhou, Tang, Hou: "Sodium aescinate significantly suppress postoperative peritoneal adhesion by inhibiting the RhoA/ROCK signaling pathway." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 69, pp. 153193, (2020) (PubMed).

Zhong, Zhang, Xu, Zhou, Liu, Ye, Zhang, Qiao, Wang, Ran, Guo: "Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy." in: ACS nano, Vol. 13, Issue 3, pp. 3387-3403, (2019) (PubMed).

Hu, Chang, Zhang, Wang, Lei, Li, Ren, Ji: "Mechanical Adaptability of the MMP-Responsive Film Improves the Functionality of Endothelial Cell Monolayer." in: Advanced healthcare materials, Vol. 6, Issue 14, (2018) (PubMed).

Gerenu, Martisova, Ferrero, Carracedo, Rantamäki, Ramirez, Gil-Bea: "Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits." in: Biochimica et biophysica acta, Vol. 1863, Issue 4, pp. 991-1001, (2017) (PubMed).

Joseph, Tholanikunnel, Kaplan: "Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema." in: The Journal of allergy and clinical immunology, Vol. 140, Issue 1, pp. 170-176, (2017) (PubMed).

Gao, Wang, Xu: "Alteration of Hemostatic Parameters in Patients with Different Levels of Subclinical Hypothyroidism and the Effect of L-thyroxine Treatment." in: Annals of clinical and laboratory science, Vol. 47, Issue 1, pp. 29-35, (2017) (PubMed).

Gowert, Klier, Reich, Reusswig, Donner, Keitel, Häussinger, Elvers: "Defective Platelet Activation and Bleeding Complications upon Cholestasis in Mice." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 6, pp. 2133-2149, (2017) (PubMed).

Santus, Barresi, Mingozzi, Broggi, Orlandi, Stamerra, Vai, Martorana, Polissi, Köhler, Liu, Zanoni, Granucci: "Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems." in: Science immunology, Vol. 2, Issue 15, (2017) (PubMed).

Synonyme und alternative Namen zu PLAT

plasminogen activator, tissue type (PLAT), plasminogen activator, tissue (Plat), plasminogen activator, tissue type (Plat), plasminogen activator, tissue (PLAT), plasminogen activator, tissue (plat), plasminogen activator, tissue type (plat), chromosome 20 open reading frame 181 (C20orf181), plasminogen activator, tissue L homeolog (plat.L), AU020998, AW212668, D8Ertd2e, PATISS, Plat, plat, T-PA, t-pa, TPA, tPA, tpa

Bezeichner auf Proteinebene für PLAT

  • alteplase
  • plasminogen activator, tissue type
  • reteplase
  • t-plasminogen activator
  • tissue plasminogen activator (t-PA)
  • tissue-type plasminogen activator
  • t-PA
  • tissue plasminogen activator
  • tPA
  • T-plasminogen activator
  • plasminogen activator, tissue
  • tissue-type plasminogen activator-like
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