ASK1 Antikörper (C-Term)
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- Target Alle ASK1 (MAP3K5) Antikörper anzeigen
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ASK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HLNSSGTNTE DSELTDWLRV NGADEDTISR FLAEDYTLLD VLYYVTRDDL KCLRLRGGML CTLWKAIIDF RNKQT
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1300 to the C-terminus of human MAP3K5 (NP_005914.1).
- Isotyp
- IgG
- Top Product
- Discover our top product MAP3K5 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
- Andere Bezeichnung
- MAP3K5 (MAP3K5 Produkte)
- Synonyme
- ASK1 antikoerper, MAPKKK5 antikoerper, MEKK5 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MUD21.11 antikoerper, MUD21_11 antikoerper, 7420452D20Rik antikoerper, ASK antikoerper, Mekk5 antikoerper, Ask1 antikoerper, RGD1306565 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MAP3K5 antikoerper, MAPKKK5 antikoerper, Map3k5 antikoerper, map3k5 antikoerper
- Hintergrund
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells, MAPKKK5 does not activate MAPK/ERK.,MAP3K5,ASK1,MAPKKK5,MEKK5,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Actins,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Hypertrophy,MAP3K5
- Molekulargewicht
- 69 kDa/154 kDa
- Gen-ID
- 4217
- UniProt
- Q99683
- Pathways
- MAPK Signalweg, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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