ASK1 Produkte
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
Kategorien
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008].
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Ausgewählte ASK1 Kategorien
ASK1 Antikörper
High quality antibodies with extensive validation data.
ASK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ASK1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ASK1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), FACS
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN683128
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN969273
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (5)
Kat. Nr.
ABIN517859
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ASK1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6957867
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968654
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968655
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ASK1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124004
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310221
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3093680
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ASK1 Produkten
: "Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells." in: Cells, Vol. 8, Issue 10, (2020) (PubMed).: "Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways." in: Frontiers in cellular neuroscience, Vol. 13, pp. 190, (2019) (PubMed).
: "Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 83, (2019) (PubMed).
: "Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway." in: Cell death discovery, Vol. 4, pp. 47, (2018) (PubMed).
: "Differential expression of survival proteins during decreased intracellular oxygen tension in brain endothelial cells of grey mullets." in: Marine pollution bulletin, Vol. 115, Issue 1-2, pp. 421-428, (2017) (PubMed).
: "Differential regulation of pro- and antiapoptotic proteins in fish adipocytes during hypoxic conditions." in: Fish physiology and biochemistry, Vol. 42, Issue 3, pp. 919-34, (2016) (PubMed).
: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, (2015) (PubMed).
: "Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium." in: The Biochemical journal, Vol. 465, Issue 3, pp. 503-15, (2015) (PubMed).
: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).
: "Heat-shock protein 70 modulates apoptosis signal-regulating kinase 1 in stressed hepatocytes of Mugil cephalus." in: Fish physiology and biochemistry, Vol. 40, Issue 5, pp. 1573-85, (2014) (PubMed).
Synonyme und alternative Namen zu ASK1
mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mitogen-activated protein kinase kinase kinase 5 (MAPKKK5), mitogen-activated protein kinase kinase kinase 5 (Map3k5), mitogen-activated protein kinase kinase kinase 5 (map3k5), 7420452D20Rik, ASK, ASK1, Ask1, MAPKKK5, MEKK5, Mekk5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11, RGD1306565Bezeichner auf Proteinebene für ASK1
- ASK-1
- MAP/ERK kinase kinase 5
- MAPK/ERK kinase kinase 5
- MEK kinase 5
- MEKK 5
- apoptosis signal regulating kinase 1
- apoptosis signal-regulating kinase 1
- mitogen activated protein kinase kinase kinase 5
- mitogen-activated protein kinase kinase kinase 5
- mitogen-activated protein kinase kinase kinase 5 pseudogene
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