CMA1 Antikörper (AA 81-247)

Produktnummer ABIN6138762

Produktdetails anti-CMA1 Antikörper

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Bindungsspezifität: AA 81-247

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ITEEEDTWQK LEVIKQFRHP KYNTSTLHHD IMLLKLKEKA SLTLAVGTLP FPSQFNFVPP GRMCRVAGWG RTGVLKPGSD TLQEVKLRLM DPQACSHFRD FDHNLQLCVG NPRKTKSAFK GDSGGPLLCA GVAQGIVSYG RSDAKPPAVF TRISHYRPWI NQILQAN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (Mast Cell Chymase (CMA1)) (NP_001827.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Andere Bezeichnung: CMA1 (CMA1 Produkte)

Synonyme: CYH antikoerper, MCT1 antikoerper, chymase antikoerper, MMCP-5 antikoerper, Mcp-5 antikoerper, Mcp5 antikoerper, Mcpt5 antikoerper, MCP3P antikoerper, CMA1 antikoerper, Chymase antikoerper, chymase 1 antikoerper, chymase 1, mast cell antikoerper, chymase-like antikoerper, CMA1 antikoerper, Cma1 antikoerper, LOC100008644 antikoerper

Hintergrund: This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.,CMA1,CYH,MCT1,chymase,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,CMA1

Molekulargewicht: 14 kDa/27 kDa

Gen-ID: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis