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CMA1 Antikörper

CMA1 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073506
  • Target Alle CMA1 Antikörper anzeigen
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Reaktivität
    • 33
    • 20
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 41
    • 9
    • 1
    • 1
    Kaninchen
    Klonalität
    • 34
    • 18
    Polyklonal
    Konjugat
    • 26
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CMA1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 21
    • 18
    • 9
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse Chymase
    Top Product
    Discover our top product CMA1 Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Andere Bezeichnung
    Mast Cell Chymase (CMA1 Produkte)
    Synonyme
    CYH antikoerper, MCT1 antikoerper, chymase antikoerper, MMCP-5 antikoerper, Mcp-5 antikoerper, Mcp5 antikoerper, Mcpt5 antikoerper, MCP3P antikoerper, CMA1 antikoerper, Chymase antikoerper, chymase 1 antikoerper, chymase 1, mast cell antikoerper, chymase-like antikoerper, CMA1 antikoerper, Cma1 antikoerper, LOC100008644 antikoerper
    Hintergrund
    This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
    Gen-ID
    17228
    NCBI Accession
    NP_034910
    UniProt
    P21844
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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