CMA1 Produkte
(Chymase 1, Mast Cell (CMA1))
Kategorien
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008].
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Ausgewählte CMA1 Kategorien
CMA1 Antikörper
High quality antibodies with extensive validation data.
CMA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CMA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CMA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN768626
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7073506
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6263136
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CMA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6954794
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6954795
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6954796
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CMA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3077902
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3133314
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Dog
Source
Yeast
Validierungen
- (2)
Kat. Nr.
ABIN7478926
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CMA1 Produkten
: "Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury." in: Science advances, Vol. 6, Issue 12, pp. eaay6314, (2020) (PubMed).: "Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 120, (2019) (PubMed).
: "A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis. ..." in: Nature communications, Vol. 8, pp. 14017, (2017) (PubMed).
: "Mast Cell-Derived Tryptase in Geographic Atrophy." in: Investigative ophthalmology & visual science, Vol. 58, Issue 13, pp. 5887-5896, (2017) (PubMed).
: "THE AUTOCRINE ROLE OF TRYPTASE IN PRESSURE OVERLOAD-INDUCED MAST CELL ACTIVATION, CHYMASE RELEASE AND CARDIAC FIBROSIS." in: IJC metabolic & endocrine, Vol. 10, pp. 16-23, (2016) (PubMed).
: "Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162644, (2016) (PubMed).
: "GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number." in: Biochemical and biophysical research communications, Vol. 459, Issue 1, pp. 131-6, (2015) (PubMed).
: "Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 27, Issue 6, pp. 764-74, (2015) (PubMed).
: "Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog." in: PLoS ONE, Vol. 9, Issue 4, pp. e94732, (2014) (PubMed).
: "Mediators of mast cells in bullous pemphigoid and dermatitis herpetiformis." in: Mediators of inflammation, Vol. 2014, pp. 936545, (2014) (PubMed).
Synonyme und alternative Namen zu CMA1
chymase 1 (CMA1), chymase 1 (Cma1), chymase 1, mast cell (CMA1), chymase 1, mast cell (Cma1), chymase-like (LOC100008644), chymase, Chymase, CMA1, CYH, Mcp-5, MCP3P, Mcp5, Mcpt5, MCT1, MMCP-5Bezeichner auf Proteinebene für CMA1
- alpha-chymase
- chymase
- chymase 1 preproprotein transcript E
- chymase 1 preproprotein transcript I
- chymase, heart
- chymase, mast cell
- mast cell protease I
- mast cell chymase
- serine protease
- SMCP-2
- mast cell protease 2
- mast cell chymase 1
- mast cell protease 5
- mast cell protease 3
- mast cell protease III
- rMCP-3
- rMCP-5
- rMCP-III
- chymase 1, mast cell
- Alpha-chymase
- LOW QUALITY PROTEIN: chymase
- chymase like protein
- preprochymase
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