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CHEK2 Antikörper (pThr68)

Name: CHEK2 Antikörper (pThr68)
SKU: ABIN5961583
Price: 449 EUR
Availability: InStock

CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Western Blotting (WB) image for anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody (ABIN5961583) (CHEK2 Antikörper (pThr68))

1 image

Produktnummer ABIN5961583

Datenblatt (PDF)

Target Alle CHEK2 Antikörper anzeigen

CHEK2 (Checkpoint Kinase 2 (CHEK2))
Bindungsspezifität
28

24

21

17

16

15

15

15

9

8

8

8

7

7

7

6

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr68
Reaktivität
253

97

83

16

14

7

6

5

2

2

1

1

1
Human, Maus, Ratte
Wirt
232

21

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
226

29
Polyklonal
Konjugat
111

14

12

12

12

12

12

12

9

9

7

7

7

7

7

2

2

1
Dieser CHEK2 Antikörper ist unkonjugiert
Applikation
202

80

79

71

37

35

31

26

22

19

16

5

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

CDS 1,Cds1,Cds1 homolog,Checkpoint kinase 2,Checkpoint like protein CHK2,CHEK 2,Chek2,Chk 2,CHK2 checkpoint homolog (S. pombe),CHK2 checkpoint homolog,CHK2,hCds1,HuCds 1,LFS 2,LFS2,PP1425,RAD 53,RAD53,Rad53 homolog,Serine/threonine protein kinase Chk2,Serine/threonine-protein kinase Chk2

Aufreinigung

Affinity purification

Immunogen

Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68

Isotyp

IgG

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CHEK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-220) antibody
CHEK2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Affe, Hund WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 10G7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IF, IHC (p), IP, FACS Wirt: Maus Monoclonal 5C4 unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Andere Bezeichnung

CHEK2 (CHEK2 Produkte)

Synonyme

CDS1 antikoerper, CHK2 antikoerper, HuCds1 antikoerper, LFS2 antikoerper, PP1425 antikoerper, RAD53 antikoerper, hCds1 antikoerper, fa66f08 antikoerper, wu:fa66f08 antikoerper, zgc:55865 antikoerper, Cds1 antikoerper, HUCDS1 antikoerper, Rad53 antikoerper, Chk2 antikoerper, cds1 antikoerper, chek2 antikoerper, chk2 antikoerper, hucds1 antikoerper, lfs2 antikoerper, pp1425 antikoerper, rad53 antikoerper, checkpoint kinase 2 antikoerper, serine/threonine-protein kinase chk2 antikoerper, checkpoint kinase 2 L homeolog antikoerper, CHEK2 antikoerper, chek2 antikoerper, Chek2 antikoerper, MCYG_07308 antikoerper, chek2.L antikoerper

Hintergrund

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

Molekulargewicht

61kDa

Gen-ID

11200

UniProt

O96017

Pathways

p53 Signalweg, Apoptose, Zellzyklus