CMA1 Antikörper

Produktnummer ABIN5958200

Produktdetails anti-CMA1 Antikörper

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Alpha-chymase,Chymase 1,Chymase 1 mast cell,chymase 1 preproprotein transcript E,chymase 1 preproprotein transcript I,Chymase,Chymase,heart,Chymase,mast cell,CMA1,CMA1,CYH,CYM,EC 3.4.21.39,Mast cell chymase 1,Mast cell protease 3,Mast cell protease 5,Mast cell protease I,Mast cell protease III,Mcp-5,MCP3P,Mcpt5,MCT1,MGC119890,MGC119891,MMCP-5

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human Chymase.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Andere Bezeichnung: Chymase (CMA1 Produkte)

Synonyme: CYH antikoerper, MCT1 antikoerper, chymase antikoerper, MMCP-5 antikoerper, Mcp-5 antikoerper, Mcp5 antikoerper, Mcpt5 antikoerper, MCP3P antikoerper, CMA1 antikoerper, Chymase antikoerper, chymase 1 antikoerper, chymase 1, mast cell antikoerper, chymase-like antikoerper, CMA1 antikoerper, Cma1 antikoerper, LOC100008644 antikoerper

Hintergrund: This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.CMA1 (Chymase 1) is a Protein Coding gene. Diseases associated with CMA1 include Urticaria Pigmentosa and Urticaria. Among its related pathways are Degradation of the extracellular matrix and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is GZMB.

Molekulargewicht: 27kDa

Gen-ID: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis