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ATM Antikörper (pSer1981)
ATM
Reaktivität: Human, Maus
WB, ELISA, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5955782
Produktdetails anti-ATM Antikörper
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Target
Alle ATM Antikörper anzeigen
ATM
(Ataxia Telangiectasia Mutated (ATM))
Bindungsspezifität
Alle Epitope für ATM Antikörper
pSer1981
Reaktivität
Alle Reaktivitäten für ATM Antikörper
Human, Maus
Wirt
Alle Wirte für ATM Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ATM Antikörper
Polyklonal
Konjugat
Alle Konjugate für ATM Antikörper
Dieser ATM Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ATM Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
A-T mutated,A-T mutated homolog,AT mutated,AT1,ATA,Ataxia telangiectasia mutated,Ataxia telangiectasia mutated gene,Ataxia telangiectasia mutated homolog (human),Ataxia telangiectasia mutated homolog,ATC,ATD,ATDC,ATE,ATM,ATM serine/threonine kinase,ATM,DKFZp781A0353,MGC74674,OTTHUMP00000232981,Serine protein kinase ATM,Serine-protein kinase ATM,Serine/threonine-protein kinase ATM,Tefu,TEL1,TEL1,telomere maintenance 1,homolog,TELO1,Telomere fusion protein
Aufreinigung
Affinity purification
Immunogen
Synthesized peptide derived from human Atm around the phosphorylation site of Ser1981
Isotyp
IgG
Top Product
Discover our top product ATM Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:20000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu ATM
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Target
ATM
(Ataxia Telangiectasia Mutated (ATM))
Andere Bezeichnung
ATM (ATM Produkte )
Synonyme
ATM antikoerper, Atm antikoerper, CG6535 antikoerper, Dmel\\CG6535 antikoerper, Tefu antikoerper, atm antikoerper, atm/tefu antikoerper, dATM antikoerper, tef antikoerper, Xatm antikoerper, at1 antikoerper, atdc antikoerper, tel1 antikoerper, telo1 antikoerper, AT1 antikoerper, ATA antikoerper, ATC antikoerper, ATD antikoerper, ATDC antikoerper, ATE antikoerper, TEL1 antikoerper, TELO1 antikoerper, AI256621 antikoerper, C030026E19Rik antikoerper, telomere fusion antikoerper, ATM serine/threonine kinase L homeolog antikoerper, ATM serine/threonine kinase antikoerper, ataxia telangiectasia mutated antikoerper, ataxia telangiectasia mutated (atm) antikoerper, serine/threonine-protein kinase ATM antikoerper, tefu antikoerper, atm.L antikoerper, atm antikoerper, ATM antikoerper, EDI_100660 antikoerper, CpipJ_CPIJ001772 antikoerper, BDBG_08252 antikoerper, PAAG_02532 antikoerper, MCYG_05088 antikoerper, VDBG_06833 antikoerper, ACLA_015700 antikoerper, LOC5565620 antikoerper, MGYG_07634 antikoerper, PGTG_14279 antikoerper, Atm antikoerper
Hintergrund
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Gen-ID
472
UniProt
Q13315
Pathways
p53 Signalweg , Apoptose , DNA Reparatur , Inositol Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus
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