IL1R1 Antikörper

Produktnummer ABIN5706822

Produktdetails anti-IL1R1 Antikörper

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Reaktivität: Human, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktmerkmale:

Synonyms: IL1RT1 antibody, Interleukin 1 receptor alpha type 1 antibody, Interleukin 1 receptor antagonist protein (IRAP) antibody, Antigen CD121a antibody, CD121A antibody, CD121a antigen antibody, D2S1473 antibody, IL 1 antibody, rabbit anti-IL-1 Receptor Type I Antibody, rabbit anti-interleukin-1 Receptor Type I Antibody

Background: IL-1 Receptor Type I is a cytokine receptor which binds interleukin 1. Anti-IL-1 Receptor Type I antibody is ideal for researchers interested in Immunology, Signal Transduction and Cancer.

Gene Name: IL1R1

Aufreinigung: This antiserum has been heated to 56°C for 30 minutes.  The antiserum is directed against the extracellular domain of the human IL-1R type I, but precipitates the intact receptor expressed on human cells.   In general, this antibody also detects primate IL-1RI.  The antibody does not recognize human IL-1, IL-1Ra or IL-1R type II.  In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type I (also called soluble IL-1R type I or ''decoy'' receptor) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.

Immunogen:

Immunogen: IL-1 Receptor Type I Antibody was prepared by repeated immunizations with recombinant human IL-1R type I.

Immunogen Type: Recombinant Protein

Anwendungsinformationen

Applikationshinweise:

Flow Cytometry Dilution: User Optimized

Immunohistochemistry Dilution: User Optimized

Application Note: This antiserum against anti-Human IL-1 Receptor Type I (IL-1RI) has been tested for use in ELISA,  radioimmunoassays and immunoprecipitation.  Reactivity in other immunoassays is unknown.This product has been assayed for the ability to immunoprecipitate antigen.  A dilution range of 1:400 to 1:800 is suggested for this immunoassay.  For immunoprecipitation, pre-clearing with a non-specific rabbit IgG is helpful to reduce background.  This product has been assayed by ELISA against soluble (extracellular) IL-1RI using HRP Conjugated Anti-Rabbit IgG [H&L] (Goat) (code # 611-1302) and ABTS as a substrate for 30 minutes at room temperature.  A working dilution range of 1:1,000 to 1:2000 is suggested for this product.  This product has been assayed by radioimmunoassay against antigen.  A dilution of 1:8,000 is suggested for this immunoassay. 

Neutralization Dilution: User Optimized

Western Blot Dilution: User Optimized

Immunoprecipitation Dilution: User Optimized

ELISA Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 84 mg/mL

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride,  pH 7.2

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 12 months

Details zu IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Andere Bezeichnung: IL-1 Receptor Type I (IL1R1 Produkte)

Synonyme: CD121A antikoerper, D2S1473 antikoerper, IL-1R-alpha antikoerper, IL1R antikoerper, IL1RA antikoerper, P80 antikoerper, CD121a antikoerper, CD121b antikoerper, IL-iR antikoerper, Il1r-1 antikoerper, DER4 antikoerper, Fit-1 antikoerper, Ly84 antikoerper, ST2L antikoerper, St2 antikoerper, St2-rs1 antikoerper, T1 antikoerper, T1/ST2 antikoerper, interleukin 1 receptor type 1 antikoerper, interleukin 1 receptor, type I antikoerper, interleukin 1 receptor-like 1 antikoerper, IL1R1 antikoerper, Il1r1 antikoerper, Il1rl1 antikoerper

Gen-ID: 3554

UniProt: P14778

Pathways: NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints