IL1R1 Antikörper (AA 18-320)

Produktnummer ABIN7156745

Produktdetails anti-IL1R1 Antikörper

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Bindungsspezifität: AA 18-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Andere Bezeichnung: IL1R1 (IL1R1 Produkte)

Synonyme: CD121A antikoerper, D2S1473 antikoerper, IL-1R-alpha antikoerper, IL1R antikoerper, IL1RA antikoerper, P80 antikoerper, CD121a antikoerper, CD121b antikoerper, IL-iR antikoerper, Il1r-1 antikoerper, DER4 antikoerper, Fit-1 antikoerper, Ly84 antikoerper, ST2L antikoerper, St2 antikoerper, St2-rs1 antikoerper, T1 antikoerper, T1/ST2 antikoerper, interleukin 1 receptor type 1 antikoerper, interleukin 1 receptor, type I antikoerper, interleukin 1 receptor-like 1 antikoerper, IL1R1 antikoerper, Il1r1 antikoerper, Il1rl1 antikoerper

Hintergrund:

Background: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Aliases: Antigen CD121a antibody, CD121 antigen-like family member A antibody, CD121a antibody, CD121a antigen antibody, D2S1473 antibody, IL 1 antibody, IL 1R 1 antibody, IL 1R alpha antibody, IL 1RT1 antibody, IL-1R-1 antibody, IL-1R-alpha antibody, IL-1RT-1 antibody, IL-1RT1 antibody, IL1 inhibitor antibody, IL1 Receptor I antibody, IL1R antibody, IL1R1 antibody, IL1R1_HUMAN antibody, IL1RA antibody, IL1RN antibody, IL1RT1 antibody, Interleukin 1 receptor alpha type 1 antibody, Interleukin 1 receptor antagonist protein (IRAP) antibody, Interleukin 1 receptor type I antibody, Interleukin receptor 1 antibody, Interleukin-1 receptor alpha antibody, Interleukin-1 receptor type 1 antibody, Interleukin-1 receptor type I antibody, p80 antibody

UniProt: P14778

Pathways: NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints