Androgen Receptor Antikörper

Produktnummer ABIN5680093

Produktdetails anti-Androgen Receptor Antikörper

Target: Androgen Receptor (AR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Androgen Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Human androgen receptor, 110 kDa protein in lysate of LNCP cell line.

Kreuzreaktivität (Details): Human

Produktmerkmale: The antibody to androgen receptors binds to these proteins in nuclei of typical normal tissues. Over-expression may be observed in tumours like prostate carcinoma and osteosarcoma. For information transmission to the target cells male steroid hormones like Testosterone and DHT require a specific receptor. This specific receptor, called androgen receptor, is found in numerous human tissues like skin, mucous membranes, seminal vesicles, prostate gland and testis. Androgen receptors will also be found in human tumours like prostate carcinoma, osteosarcoma and others. In prostate carcinoma the clinical relevance has been proven by castration and androgen deprivation by Gn-RH-agonist and -antagonist treatment. In many cases androgen deprivation slows down tumour growth in androgen-dependent prostate carcinoma. Human androgen receptor, 110 kDa protein in lysate of LNCP cell line..

Aufreinigung: Antibody solution

Immunogen: Synthetic peptide

Klon: F39-4-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G ,Testis,IHC(C, P),60 min at RT,(liquid conc.) 1:5 - 1:20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: stabilizing phosphate buffer  pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μL working solution / test)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Androgen Receptor

Target: Androgen Receptor (AR)

Andere Bezeichnung: Androgen Receptor (AR Produkte)

Synonyme: AIS antikoerper, DHTR antikoerper, HUMARA antikoerper, HYSP1 antikoerper, KD antikoerper, NR3C4 antikoerper, SBMA antikoerper, SMAX1 antikoerper, TFM antikoerper, AW320017 antikoerper, Tfm antikoerper, Andr antikoerper, AR antikoerper, androgen receptor antikoerper, AR antikoerper, Ar antikoerper, ar antikoerper

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding