Androgen Receptor Antikörper

Produktnummer ABIN1724724

Produktdetails anti-Androgen Receptor Antikörper

Target: Androgen Receptor (AR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Androgen Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human AR expressed in E. coli.

Klon: 2H8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Androgen Receptor Antikörper (ABIN1724724)

Yu, Han, Shao, Wu, Zhao, Liu, Sun, Tang, Xia: "Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo." in: Chinese medical journal, Vol. 122, Issue 22, pp. 2779-83, (2009) (PubMed).

Hsu, Lan, Tsai, Ou, Cheng, Tsai, Kang, Tung, Wong, Huang: "Expression of androgen receptor in human placentas from normal and preeclamptic pregnancies." in: Taiwanese journal of obstetrics & gynecology, Vol. 48, Issue 3, pp. 262-7, (2009) (PubMed).

Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: "DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells." in: Cancer research, Vol. 67, Issue 10, pp. 4630-7, (2007) (PubMed).

Details zu Androgen Receptor

Target: Androgen Receptor (AR)

Andere Bezeichnung: Androgen receptor (AR Produkte)

Synonyme: AIS antikoerper, DHTR antikoerper, HUMARA antikoerper, HYSP1 antikoerper, KD antikoerper, NR3C4 antikoerper, SBMA antikoerper, SMAX1 antikoerper, TFM antikoerper, AW320017 antikoerper, Tfm antikoerper, Andr antikoerper, AR antikoerper, androgen receptor antikoerper, AR antikoerper, Ar antikoerper, ar antikoerper

Hintergrund:

Description: The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Aliases: NR3C4, KD, AIS, SMAX1, HUMARA, AR

Molekulargewicht: 110 kDa

Gen-ID: 367

HGNC: 367

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding