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Androgen Receptor Antikörper (pSer578)

AR Reaktivität: Human, Maus, Ratte IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN730123
  • Target Alle Androgen Receptor (AR) Antikörper anzeigen
    Androgen Receptor (AR)
    Bindungsspezifität
    • 21
    • 20
    • 19
    • 18
    • 17
    • 17
    • 15
    • 13
    • 13
    • 12
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer578
    Reaktivität
    • 304
    • 92
    • 88
    • 29
    • 19
    • 17
    • 15
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    Human, Maus, Ratte
    Wirt
    • 255
    • 52
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 245
    • 63
    Polyklonal
    Konjugat
    • 117
    • 27
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Androgen Receptor Antikörper ist unkonjugiert
    Applikation
    • 183
    • 89
    • 64
    • 58
    • 53
    • 40
    • 32
    • 22
    • 19
    • 17
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    This phosphorylation site is homologous to that of Ser558 in Mouse and Ser561 in Rat.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser578 [CG(p-S)CK]
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Androgen Receptor (AR)
    Andere Bezeichnung
    Androgen Receptor (AR Produkte)
    Synonyme
    AIS antikoerper, DHTR antikoerper, HUMARA antikoerper, HYSP1 antikoerper, KD antikoerper, NR3C4 antikoerper, SBMA antikoerper, SMAX1 antikoerper, TFM antikoerper, AW320017 antikoerper, Tfm antikoerper, Andr antikoerper, AR antikoerper, androgen receptor antikoerper, AR antikoerper, Ar antikoerper, ar antikoerper
    Hintergrund

    Synonyms: KD, AIS, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1, HUMARA, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, AR

    Background: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

    Gen-ID
    367
    UniProt
    P10275
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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