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Androgen Receptor Produkte

(Androgen Receptor (AR))
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte Androgen Receptor Kategorien

Androgen Receptor Antikörper

High quality antibodies with extensive validation data.

Androgen Receptor ELISA Kits

Reliable ELISA kits for a wide range of species.

Androgen Receptor Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Androgen Receptor Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF, ICC
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN1871059
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN2857043
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN1724724
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Androgen Receptor ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964823
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974982
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953700
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Androgen Receptor Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121827
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121826
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345428
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Androgen Receptor Produkten

Huang, Zheng, Pan, Wu, Su, Li, Wu, Sun: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." in: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).

Xue, Zhang, Wang, Zhang, Xiang, Wang, Wang, Li, Zhang, Zou, Wang, Wu, Lu, Chen, Ding, Li, Xu: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." in: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).

Pizon, Lux, Pachmann, Pachmann, Schott: "Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer." in: Journal of translational medicine, Vol. 16, Issue 1, pp. 356, (2018) (PubMed).

Huang, Wu, Su, Yan, Sun: "Effects of low dose of bisphenol A on the proliferation and mechanism of primary cultured prostate epithelial cells in rodents." in: Oncology letters, Vol. 14, Issue 3, pp. 2635-2642, (2017) (PubMed).

Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: "Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo." in: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 1, pp. 53-62, (2016) (PubMed).

Zhao, Jin, Zhang, Cui, Sun, Gao, Gu, Cai: "Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 980583, (2016) (PubMed).

Liu, Cheng, Pan, Hu, Xu, Meng, Wu, Xie, Yan, Sun: "Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1361-1366, (2016) (PubMed).

Zhang, Shen, Cao, Yan, Ji et al.: "Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and ..." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 905-908, (2015) (PubMed).

Liu, Liu, Fu, Wang, Zhang: "Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model." in: Oncology letters, Vol. 10, Issue 3, pp. 1819-1825, (2015) (PubMed).

McCall, Adams, Willder, Bennett, Qayyum, Orange, Underwood, Edwards: "Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients." in: International journal of molecular sciences, Vol. 14, Issue 8, pp. 16656-71, (2013) (PubMed).

Synonyme und alternative Namen zu Androgen Receptor

androgen receptor (AR), androgen receptor (Ar), androgen receptor (ar), AIS, Andr, AR, AW320017, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, Tfm

Bezeichner auf Proteinebene für Androgen Receptor

  • androgen nuclear receptor variant 2
  • dihydrotestosterone receptor
  • nuclear receptor subfamily 3 group C member 4
  • testicular feminization
  • androgen receptor (Testicular feminization), same as Tfm
  • androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
  • androgen receptor AR
  • AR-A
  • Ar beta
  • androgen receptor
  • prostate androgen receptor
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