LDHB Antikörper

Produktnummer ABIN5647182

Produktdetails anti-LDHB Antikörper

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids E237-L334 from the human protein were used as the immunogen for the LDHB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the LDHB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu LDHB

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Andere Bezeichnung: LDHB / Lactate dehydrogenase B (LDHB Produkte)

Synonyme: LDH-B antikoerper, LDH-H antikoerper, LDHBD antikoerper, TRG-5 antikoerper, AI790582 antikoerper, H-Ldh antikoerper, Ldh-2 antikoerper, Ldh2 antikoerper, ldh-h antikoerper, ldh2 antikoerper, ldhb antikoerper, ldhba antikoerper, trg-5 antikoerper, LDHB antikoerper, LDH-B-A antikoerper, wu:fa16d07 antikoerper, wu:fa20c10 antikoerper, wu:fa96a08 antikoerper, LDH-B-B antikoerper, zgc:92882 antikoerper, lactate dehydrogenase B antikoerper, lactate dehydrogenase B S homeolog antikoerper, lactate dehydrogenase Ba antikoerper, lactate dehydrogenase Bb antikoerper, LDHB antikoerper, Ldhb antikoerper, ldhb.S antikoerper, ldhb antikoerper, ldhba antikoerper, ldhbb antikoerper

Hintergrund: The LDHB gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

UniProt: P07195

Pathways: Warburg Effekt