LDHB Antikörper (C-Term)

Produktnummer ABIN2783283

Der Kaninchen Polyklonal anti-LDHB Antikörper (ABIN2783283) detektiert spezifisch LDHB in WB, IHC und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für LDHB Antikörper (C-Term) (ABIN2783283)

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-LDHB Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: LDHB Antibody - C-terminal region

Sequenz: MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against LDHB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104131

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LDHB

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Andere Bezeichnung: LDHB

Hintergrund:

Background Information: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Gene Name: lactate dehydrogenase B

Alternative Symbols: LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Protein Name: L-lactate dehydrogenase B chain

Molekulargewicht: 37kDa

Gen-ID: 3945

NCBI Accession: NP_002291

UniProt: P07195

Pathways: Warburg Effekt