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TICAM2 Antikörper (C-Term)

TICAM2 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500931
  • Target Alle TICAM2 Antikörper anzeigen
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 50
    • 16
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 47
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 51
    • 1
    Polyklonal
    Konjugat
    • 30
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TICAM2 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 24
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TICAM2 / TRAM.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    TIRP antibody was raised against a peptide corresponding to amino acids near the C- terminus of human TIRP.
    Isotyp
    IgG
    Top Product
    Discover our top product TICAM2 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 0.5 to 2 μg/mL. Immunohistochemistry on parffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Ye, Yang, Chen, Li, Jia, Su, Wang, He: "Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway." in: Stem cells international, Vol. 2017, pp. 5841814, (2017) (PubMed).

    Landais, Pelton, Streblow, DeFilippis, McWeeney, Nelson: "Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway." in: PLoS pathogens, Vol. 11, Issue 5, pp. e1004881, (2016) (PubMed).

  • Target
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Andere Bezeichnung
    TICAM2 / TRAM (TICAM2 Produkte)
    Synonyme
    MyD88-4 antikoerper, TICAM-2 antikoerper, TIRAP3 antikoerper, TIRP antikoerper, TRAM antikoerper, B430113A10 antikoerper, Tirp antikoerper, Trif antikoerper, toll like receptor adaptor molecule 2 antikoerper, toll-like receptor adaptor molecule 2 antikoerper, TICAM2 antikoerper, Ticam2 antikoerper
    Hintergrund
    TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).Synonyms: Putative NF-kappa-B-activating protein 502, TICAM-2, TIR domain-containing adapter molecule 2, TIRAP3, TIRP, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein
    Gen-ID
    353376
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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