TPP1 Antikörper (Internal Region)

Produktnummer ABIN401515

Produktdetails anti-TPP1 Antikörper

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: c-TPSVIRKRYN LTSQD

Spezifität: This antibody detects Tripeptidyl-peptidase 1 (TPP1) (Internal).

Kreuzreaktivität (Details): Species reactivity (expected):Dog, CowSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_000382.3. Genename: TPP1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 4000. Western blot: 0.3-1 μg/mL. Approx 65 kDa band observed in Human Placenta lysates(calculated MW of 61.5 kDa according to NP_000382.3).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: Tripeptidyl-Peptidase 1 (TPP1) (TPP1 Produkte)

Synonyme: cln2 antikoerper, fa01b09 antikoerper, im:7149243 antikoerper, wu:fa01b09 antikoerper, CLN2 antikoerper, LPIC antikoerper, TPP-1 antikoerper, TPP-I antikoerper, Cln2 antikoerper, tripeptidyl peptidase I antikoerper, tripeptidyl-peptidase 1 antikoerper, tripeptidyl peptidase 1 antikoerper, tpp1 antikoerper, NAEGRDRAFT_78259 antikoerper, MCYG_00184 antikoerper, MGYG_05881 antikoerper, MGYG_00757 antikoerper, TPP1 antikoerper, Tpp1 antikoerper

Hintergrund: TPP1 (Tripeptidyl peptidase I) is a lysosomal serine protease which cleaves N-terminal tripeptides from substrates. It requires substrates with an unsubstituted N-terminus. TPP1 may act as a non-specific lysosomal peptidase generating tripeptides from the breakdown products produced by lysosomal proteinases. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis.Synonyms: Cell growth-inhibiting gene 1 protein, GIG1, LPIC, Lysosomal pepstatin-insensitive protease, TPP-1, TPP-I, Tripeptidyl aminopeptidase

Gen-ID: 1200

NCBI Accession: NP_000382

UniProt: O14773

Pathways: Zellzyklus, ER-Nucleus Signaling